本文介绍了近几年山东大学进行医学物理学课程建设的改革与实践研究. 在医学物理学教学中，体现以学生为中心的教学理念，在国内主要课程平台建设开放的医学物理学MOOC，研究出版立体化新形态配套教材，建立完善教材体系，开展基于SPOC 的线上线下混合式教学，采用翻转课堂等多种有效的教学策略进行课堂教学改革. 实践表明，通过多维度的教学改革大力促进了医学物理学课程建设水平，切实提升了教学质量和效果.

The construction of medical physics course at Shandong University is introduced in this paper. Many teaching reforms are taken in medical physics in recent years. Student-centered teaching philosophy runs throng the teaching process. Medical physics teaching resources are put on MOOC platform and opened to everyone. New form textbook is studied and will be published，in which a perfect teaching textbook system is established. In addition， the blended teaching mode based on SPOC online course is used and flipped class mode is tried in the face-to-face class. Furthermore，a variety of effective teaching methods are employed in classes. Research results have showed that the multi-dimensional teaching reforms have greatly promoted the level of medical physics course construction and improved the quality and effect of teaching at the same time.