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论离心分离理论中匀速运动处理的合理性

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  • 中国科学院 生物物理研究所,北京100101
郭震东(1996—),男,湖北宜昌人,中国科学院生物物理研究所2022届硕士.E-mail:guozhendong19@mails.ucas.ac.cn

收稿日期: 2023-05-10

  修回日期: 2023-08-31

  网络出版日期: 2024-06-28

On the rationality of the uniform motion treatment in the centrifugal separation theory

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  • Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

Received date: 2023-05-10

  Revised date: 2023-08-31

  Online published: 2024-06-28

摘要

离心技术是借助离心力将颗粒物质根据沉降系数的差异实现分离的实验技术,但离心分离理论中存在许多近似处理,例如:忽略科里奥利力;将颗粒物质的离心过程按照匀速运动处理. 本文将根据牛顿力学的基本原理对颗粒物质在差速离心法和沉降速率法中的离心过程进行严谨的动力学分析,并结合牛血清白蛋白(BSA)的相关参数进行数值计算,着重对匀速运动处理的合理性进行探讨.

本文引用格式

郭震东 . 论离心分离理论中匀速运动处理的合理性[J]. 大学物理, 2024 , 43(04) : 61 . DOI: 10.16854/j.cnki.1000-0712.230191

Abstract

The centrifugal technique is an experimental technique, which separates particulate matter according to the difference of the sedimentation coefficient by centrifugal force. However, numerous approximate treatments exist in the centrifugal separation theory, such as ignoring Coriolis force, treating the centrifugal process of particulate matter as a uniform motion. In this research, a rigorous kinetic analysis for the centrifugal process of particulate matter by differential centrifugation method and sedimentation velocity method is carried out according to the basic principles of Newtonian mechanics. Combining with numerical calculation of the relevant parameters of bovine serum albumin (BSA), this research focuses on the rationality of the uniform motion treatment.

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