Under the transformation of talent cultivation models in local applied undergraduate institutions, college physics courses exist numerous problems, including the disconnection between teaching content and majors, outdated teaching methods, singular evaluation systems, uneven student foundations, and so on. Taking Sichuan University of Science ＆ Engineering as an example, based on the standards of professional certification, a “one-line-five-elements” college physics curriculum system, which integrates basic theory, course-based ideological and political education, physics frontiers, practical teaching, and subject and major, has been constructed. By adopting “Internet + Education”, a blended teaching platform that combines online and offline instruction has been established, and differentiated teaching has been implemented. The reforms in college physics have made beneficial attempts in enhancing teaching quality for teachers and learning capabilities for students, which provide references for similar universities to carry out blended teaching in college physics.