The current situation of physical experiment courses in domestic medical specialty is analyzed，and an education reform practice of the physics experiment course of Peking University Health Science Center is introduced. Directed by the idea of “adhering to the basic of physics，increasing the contemporary contents，combining with applied medicine”，a ten-year education reform practice results in a new physical experimental course. This course emphasizes both medical applications and physics，and places value on both modern technology and hands on operation. It turns out that students show more interest to this physical experiment. A suggestion is put forward that emphasis should be laid on the basic of physics in the physics course construction and teaching reform for medical specialty.