Based on the two-qubit quantum computer physical model，the rule of designing quantum search algorithm nuclear magnetic resonance pulse sequence parameters is proposed through the approximate solution of the two-body the time-dependent Schrdinger equation in a rotating frame. Specified parameters are given. According to the Suzuki symmetric product-formula，the time-step evolution operator is decomposed into ordered product of some symmetric exponential operators. By using this method，the time-dependent Schrdinger equation is numerically calculated. The numerical calculation results verify that parameters and rules of designing parameter are correct.