Thomson's model of atomic scattering of the alpha particle is the most basic content，but in the teaching process，

generally only starting from the classical mechanics of alpha particle scattering theory deduction，few of error transfer

and mathematical statistics knowledge were discussed. In this paper，starting from the related theory of classical mechanics

and mathematical statistics，we calculate the probability of alpha particle large angle scattering in the experiment

of Rutherford scattering experiment. In order to show that in the teaching process should strengthen，their ability

of multidisciplinary knowledge fusion is the key step to improve students'scientific research ability.