New engineering talents are crucial in addressing the complex challenges of the future world, and the number of such talents determines the overall progress of society. The cultivation of new engineering talents requires innovative teaching design as the cornerstone. Aligned with the connotations of new engineering talent, the educational reform practice based on the Problem-Based Learning (PBL) method, conducted in large-class composed of general students, has considered the beneficial needs of students at various levels, compensating for the scarcity of teaching staff in large-scale class settings. This teaching practice has promoted the deep learning of ordinary students, expanded the beneficiary group of teaching reform, effectively achieved the goals of value shaping, knowledge imparting, and capability cultivation, and the course teaching has a distinct high-level, innovative, and challenging nature, exploring an effective new path for the cultivation of new engineering talents.